HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57517503, compound → 4-(Cyclopropylmethoxy)-3-fluorobenzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57517503 | HCID 57517503 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-(Cyclopropylmethoxy)-3-fluorobenzenamine | HCID 19627244 | 99.8% |
Reaction Steps
A mixture of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (3.00 g), 10% palladium-carbon (containing water (50%), 3.00 g) and THF (30 mL) was stirred at room temperature for 1 hr under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (2.57 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133129B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-83e46c465d924d5cb0690b86679b2380 |
| Source note | uspto-grants-2015_09 |