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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277153Generated: October 30, 2026

HCID 57517503, compound → 4-(Cyclopropylmethoxy)-3-fluorobenzenamine

https://huagongshe.com/reaction/2277153

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57517503HCID 57517503—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
Product4-(Cyclopropylmethoxy)-3-fluorobenzenamineHCID 1962724499.8%

Reaction Steps

A mixture of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (3.00 g), 10% palladium-carbon (containing water (50%), 3.00 g) and THF (30 mL) was stirred at room temperature for 1 hr under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (2.57 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-83e46c465d924d5cb0690b86679b2380
Source noteuspto-grants-2015_09