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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277273Generated: October 30, 2026

Bromoacetonitrile → N-((2S)-1-((2-(4-(cyanomethoxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoacetonitrileHCID 11534—
ReactantN-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamideHCID 86731330—
ProductN-((2S)-1-((2-(4-(cyanomethoxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamideHCID 86731352—

Reaction Steps

Using N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide and bromoacetonitrile, and in the same manner as in Example 5, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-b856113cd46046d6a5b04c9768b4b18d
Source noteuspto-grants-2015_09