HCID 178461781, compound → HCID 178461779, compound

Participants

Reaction Steps

A mixture of tert-butyl ((2S)-1-((4-hydroxy-5-nitropyridin-2-yl)oxy)propan-2-yl)carbamate (3.84 g) and 10% palladium/carbon (containing water (50%), 0.40 g) and methanol (50 mL) was stirred at room temperature for 15 hr under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (3.35 g).

Provenance & Evidence