((1R)-2,2-difluorocyclopropyl)methyl 4-nitrobenzenesulfonate → N-((2S)-1-((2-(5-(((1R)-2,2-difluorocyclopropyl)methoxy)pyridin-2-yl)-7-fluoro[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide

Participants

Reaction Steps

Using N-((2S)-1-((2-(5-(benzyloxy)pyridin-2-yl)-7-fluoro[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide and ((1R)-2,2-difluorocyclopropyl)methyl 4-nitrobenzenesulfonate, and in the same manner as in Step A of Example 4 and Example 5, the title compound was obtained.

Provenance & Evidence