HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tolylboronic acid → 2-[1-methyl-5-(4-methylphenyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tolylboronic acid | HCID 79799 | — |
| Reactant | 2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile | HCID 90408144 | — |
| Product | 2-[1-methyl-5-(4-methylphenyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile | HCID 90407259 | 54% |
Reaction Steps
The title compound was prepared in 54% yield from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and p-tolylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C17H14N4, 275. Found, 275.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-581a27c04d704d38b80427f60dd5ba0c |
| Source note | uspto-grants-2015_09 |