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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277442Generated: October 31, 2026

Boronic acid, (4-ethylphenyl)- → 2-[5-(4-ethylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrile

https://huagongshe.com/reaction/2277442

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic acid, (4-ethylphenyl)-HCID 2734352—
Reactant2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrileHCID 90408144—
Product2-[5-(4-ethylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrileHCID 9040738790%

Reaction Steps

The title compound was prepared in 90% yield from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-ethylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C18H16N4, 289. Found, 289.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-f090cd57b710492498a41359d5498059
Source noteuspto-grants-2015_09