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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277447Generated: October 30, 2026

3-(Methylcarbamoyl)benzeneboronic acid → 3-[4-(4-cyanopyridin-2-yl)-1-methyl-1H-imidazol-5-yl]-N-methylbenzamide

https://huagongshe.com/reaction/2277447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylcarbamoyl)benzeneboronic acidHCID 2773524—
Reactant2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrileHCID 90408144—
Product3-[4-(4-cyanopyridin-2-yl)-1-methyl-1H-imidazol-5-yl]-N-methylbenzamideHCID 90407859—

Reaction Steps

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 3-(N-methylaminocarbonyl)phenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C18H15N5O, 318. Found, 318.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-6de7efb184a9492db354146d0d8fd531
Source noteuspto-grants-2015_09