{4-[1-(Hydroxymethyl)cyclopropyl]phenyl}boronic acid → HCID 90407600, compound

HRID 2277454Notes

Reaction equation

HRID 2277454 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[OH:16][CH2:17][C:18]1([C:21]2[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=2)[CH2:20][CH2:19]1>>[OH:16][CH2:17][C:18]1([C:21]2[CH:26]=[CH:25][C:24]([C:2]3[N:6]([CH3:7])[CH:5]=[N:4][C:3]=3[C:8]3[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=3)=[CH:23][CH:22]=2)[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 46739662{4-[1-(Hydroxymethyl)cyclopropyl]phenyl}boronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407600HCID 90407600, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-(1-(hydroxymethyl)cyclopropyl)phenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H18N4O, 331. Found, 331.

Sources & evidence

ORD record
ord-8f6b66293d154dc4acb58a09e52236a0
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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