(4-Pyrrolidin-1-ylphenyl)boronic acid → HCID 90407555, compound

HRID 2277455Notes

Reaction equation

HRID 2277455 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[N:16]1([C:21]2[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=2)[CH2:20][CH2:19][CH2:18][CH2:17]1>>[CH3:7][N:6]1[C:2]([C:24]2[CH:23]=[CH:22][C:21]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)=[CH:26][CH:25]=2)=[C:3]([C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)[N:4]=[CH:5]1

Participants

3

Reactant 2

HCID 4192670(4-Pyrrolidin-1-ylphenyl)boronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407555HCID 90407555, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-pyrrolidinophenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H19N5, 330. Found, 330.

Sources & evidence

ORD record
ord-89d210e282f94450a37bb8b4e032b273
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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