(4-Ethynylphenyl)boronic acid → HCID 90406721, compound

HRID 2277458Notes

Reaction equation

HRID 2277458 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.B(O)(O)[C:17]1[CH:22]=[CH:21][C:20]([C:23]#[CH:24])=[CH:19][CH:18]=1>>[C:23]([C:20]1[CH:21]=[CH:22][C:17]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)=[CH:18][CH:19]=1)#[CH:24]

Participants

3

Reactant 2

HCID 23436919(4-Ethynylphenyl)boronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90406721HCID 90406721, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-(dihydroxyborophenyl)acetylene according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C18H12N4, 285. Found, 285.

Sources & evidence

ORD record
ord-126d06653d894a0abd9734861178e44b
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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