1H-Indol-6-ylboronic acid → HCID 90407014, compound

HRID 2277459Notes

Reaction equation

HRID 2277459 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[NH:16]1[C:24]2[C:19](=[CH:20][CH:21]=[C:22](B(O)O)[CH:23]=2)[CH:18]=[CH:17]1>>[NH:16]1[C:24]2[C:19](=[CH:20][CH:21]=[C:22]([C:2]3[N:6]([CH3:7])[CH:5]=[N:4][C:3]=3[C:8]3[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=3)[CH:23]=2)[CH:18]=[CH:17]1

Participants

3

Reactant 2

HCID 27632051H-Indol-6-ylboronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407014HCID 90407014, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 6-indolylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C18H13N5, 300. Found, 300.

Sources & evidence

ORD record
ord-2810923227dd443098942895ba008c7e
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

Loading…