(4-Chloro-2-methylphenyl)boronic acid → HCID 90407193, compound

HRID 2277463Notes

Reaction equation

HRID 2277463 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20](B(O)O)=[C:19]([CH3:26])[CH:18]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)=[C:19]([CH3:26])[CH:18]=1

Participants

3

Reactant 2

HCID 5017600(4-Chloro-2-methylphenyl)boronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407193HCID 90407193, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-chloro-2-methylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C17H13ClN4, 310. Found, 309, 311.

Sources & evidence

ORD record
ord-086c7788c58447bc99df64d993c34401
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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