HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(trifluoromethyl)phenylboronic Acid → 2-{5-[4-chloro-2-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-4-yl}pyridine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(trifluoromethyl)phenylboronic Acid | HCID 2763244 | — |
| Reactant | 2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile | HCID 90408144 | — |
| Product | 2-{5-[4-chloro-2-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-4-yl}pyridine-4-carbonitrile | HCID 90407788 | — |
Reaction Steps
The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-chloro-2-trifluoromethylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C17H10ClF3N4, 364. Found, 363, 365.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-7ef5b72f83a54cf1af9224cb17e60a3d |
| Source note | uspto-grants-2015_09 |