4-CHLORO-2-ETHOXYPHENYLBORONIC ACID → HCID 90407299, compound

HRID 2277469Notes

Reaction equation

HRID 2277469 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20](B(O)O)=[C:19]([O:26][CH2:27][CH3:28])[CH:18]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)=[C:19]([O:26][CH2:27][CH3:28])[CH:18]=1

Participants

3

Reactant 2

HCID 42538474-CHLORO-2-ETHOXYPHENYLBORONIC ACIDHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407299HCID 90407299, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-chloro-2-ethoxyphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C18H15ClN4O, 340. Found, 339, 341.

Sources & evidence

ORD record
ord-d6153a7f647e4d23b7c0651e277b592a
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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