1431983-70-8 → HCID 90407514, compound

HRID 2277471Notes

Reaction equation

HRID 2277471 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.CC1(C)C(C)(C)OB([C:24]2[CH:29]=[CH:28][C:27]([C:30]3([C:33]([F:36])([F:35])[F:34])[CH2:32][CH2:31]3)=[CH:26][CH:25]=2)O1>>[CH3:7][N:6]1[C:2]([C:24]2[CH:25]=[CH:26][C:27]([C:30]3([C:33]([F:34])([F:35])[F:36])[CH2:32][CH2:31]3)=[CH:28][CH:29]=2)=[C:3]([C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)[N:4]=[CH:5]1

Participants

3

Reactant 2

HCID 904070431431983-70-8HCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407514HCID 90407514, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4,4,5,5-tetramethyl-2-[4-[1-(trifluoromethyl)cyclopropyl]phenyl]-1,3,2-dioxaborolane according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H15F3N4, 369. Found, 369.

Sources & evidence

ORD record
ord-e963ef73eabb4413b6d298c6a8f15b28
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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