1-Bromo-3-methoxypropane → 2-[1-(3-methoxypropyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile

HRID 2277476Notes

Reaction equation

HRID 2277476 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Br[CH2:15][CH2:16][CH2:17][O:18][CH3:19]>>[CH3:19][O:18][CH2:17][CH2:16][CH2:15][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 5245511-Bromo-3-methoxypropaneHCID 178510201HCID 178510201, compound

Product 1

HCID 904079082-[1-(3-methoxypropyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 1-bromo-3-methoxypropane according to the procedure for the preparation of Example 35, part A. [M+H] Calc'd for C13H14N4O, 243. Found, 243.

Sources & evidence

ORD record
ord-8f3b1b1577f84103a6810427ee89fac2
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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