(3-Bromopropyl)dimethylamine hydrobromide → 2-{1-[3-(dimethylamino)propyl]-1H-imidazol-4-yl}pyridine-4-carbonitrile

HRID 2277482Notes

Reaction equation

HRID 2277482 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Br.Br[CH2:16][CH2:17][CH2:18][N:19]([CH3:21])[CH3:20]>>[CH3:20][N:19]([CH3:21])[CH2:18][CH2:17][CH2:16][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 20135846(3-Bromopropyl)dimethylamine hydrobromideHCID 178510201HCID 178510201, compound

Product 1

HCID 904075012-{1-[3-(dimethylamino)propyl]-1H-imidazol-4-yl}pyridine-4-carbonitrile

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and (3-bromopropyl)dimethylamine hydrogen bromide according to the procedure for the preparation of Example 35, part A. [M+H] Calc'd for C14H17N5, 256. Found, 256.

Sources & evidence

ORD record
ord-f659871cbc93481bb1d51a4b3a395b74
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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