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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277487Generated: October 30, 2026

Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → 2-{1-[2-(morpholin-4-yl)ethyl]-1H-imidazol-4-yl}pyridine-4-carbonitrile

https://huagongshe.com/reaction/2277487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)HCID 77210—
ReactantHCID 178510201HCID 178510201—
Product2-{1-[2-(morpholin-4-yl)ethyl]-1H-imidazol-4-yl}pyridine-4-carbonitrileHCID 90407173—

Reaction Steps

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-(2-chloroethyl)morpholine hydrogen chloride according to the procedure for the preparation of Example 43, part A. [M+H] Calc'd for C15H17N5O, 284. Found, 284.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-09aa91c316ec41a49879f0e0161c8f24
Source noteuspto-grants-2015_09