4-chloro-N-methylpiperidine → HCID 90407139, compound
Reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Cl[CH:15]1[CH2:20][CH2:19][N:18]([CH3:21])[CH2:17][CH2:16]1>>[CH3:21][N:18]1[CH2:19][CH2:20][CH:15]([N:1]2[CH:5]=[C:4]([C:6]3[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=3)[N:3]=[CH:2]2)[CH2:16][CH2:17]1Participants
3
Procedure
The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-chloro-1-methylpiperidine according to the procedure for the preparation of Example 43, part A. [M+H] Calc'd for C15H17N5, 268. Found, 268.
Sources & evidence
- ORD record
- ord-cae408582441466eb179c2594079130f
- Source dataset
- uspto-grants-2015_09
- Patent number
- US09133166B2
Reaction notes
Loading…