4-(Bromomethyl)-1-methylpiperidine--hydrogen bromide (1/1) → HCID 90407153, compound

HRID 2277491Notes

Reaction equation

HRID 2277491 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Br.Br[CH2:16][CH:17]1[CH2:22][CH2:21][N:20]([CH3:23])[CH2:19][CH2:18]1>>[CH3:23][N:20]1[CH2:21][CH2:22][CH:17]([CH2:16][N:1]2[CH:5]=[C:4]([C:6]3[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=3)[N:3]=[CH:2]2)[CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 510003374-(Bromomethyl)-1-methylpiperidine--hydrogen bromide (1/1)HCID 178510201HCID 178510201, compound

Product 1

HCID 90407153HCID 90407153, compound

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-bromomethyl-1-methylpiperidine hydrogen bromide according to the procedure for the preparation of Example 43, part A (heating to 120°). [M+H] Calc'd for C16H19N5, 282. Found, 282.

Workup

  1. temperatureA (heating to 120°)

Sources & evidence

ORD record
ord-0f07e2fe0696413faac878d17b1dcf90
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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