Furan, 2-(bromomethyl)tetrahydro- → HCID 90407840, compound

HRID 2277492Notes

Reaction equation

HRID 2277492 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.[CH2:14](Br)[CH:15]1[O:19][CH2:18][CH2:17][CH2:16]1>>[O:19]1[CH2:18][CH2:17][CH2:16][CH:15]1[CH2:14][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 14501Furan, 2-(bromomethyl)tetrahydro-HCID 178510201HCID 178510201, compound

Product 1

HCID 90407840HCID 90407840, compound

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and tetrahydrofurfuryl bromide according to the procedure for the preparation of Example 43, part A (heating to 120°). [M+H] Calc'd for C14H14N4O, 255. Found, 255.

Workup

  1. temperatureA (heating to 120°)

Sources & evidence

ORD record
ord-9e9ee135b92b4fd9a6c4b67f2bc6612c
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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