HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate → tert-butyl 2-{[4-(4-cyanopyridin-2-yl)-1H-imidazol-1-yl]methyl}pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-(bromomethyl)pyrrolidine-1-carboxylate | HCID 14821711 | — |
| Reactant | HCID 178510201 | HCID 178510201 | — |
| Product | tert-butyl 2-{[4-(4-cyanopyridin-2-yl)-1H-imidazol-1-yl]methyl}pyrrolidine-1-carboxylate | HCID 90407843 | — |
Reaction Steps
The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and tert-butyl-2-(bromomethyl)pyrrolidine-1-carboxylate according to the procedure for the preparation of Example 43, part A (heating to 120°). [M+H] Calc'd for C19H23N5O2, 354. Found, 354.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-1bd9f15f39144c298f2be5de759f8ff4 |
| Source note | uspto-grants-2015_09 |