1-(2-Chloroethyl)pyrrolidin-2-one → HCID 90408028, compound

HRID 2277504Notes

Reaction equation

HRID 2277504 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Cl[CH2:15][CH2:16][N:17]1[CH2:21][CH2:20][CH2:19][C:18]1=[O:22]>>[O:22]=[C:18]1[CH2:19][CH2:20][CH2:21][N:17]1[CH2:16][CH2:15][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 31566501-(2-Chloroethyl)pyrrolidin-2-oneHCID 178510201HCID 178510201, compound

Product 1

HCID 90408028HCID 90408028, compound

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 1-(2-chloroethyl)-2-pyrrolidinone according to the procedure for the preparation of Example 43, part A (heating to 120°). [M+H] Calc'd for C15H15N5O, 282. Found, 282.

Workup

  1. temperatureA (heating to 120°)

Sources & evidence

ORD record
ord-30b8aadf2f524048b585456fa85d7160
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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