Ammonia → HCID 178513687, compound

Participants

Reaction Conditions

Reaction Steps

2-[4-(4-methylphenyl)sulfonyl-4,5-dihydro-1,3-oxazol-5-yl]pyridine-4-carboxamide (23 g, 63.98 mmol) was added to a solution of NH3 in MeOH (5 g/120 mL) and stirred overnight at 125° C., concentrated and purified by flash column chromatography to give the title compound (5 g, 36.8%). [M+H] Calc'd for C9H8N4O, 189. Found, 189.

Provenance & Evidence