Pyridine → HCID 90408277, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]pyridine-4-carboxamide (1 eq) and pyridine (3 eq) in DCM was added TFAA (2 eq) slowly at 0° C., then the mixture was stirred for 2 hr at 0° C., the solution was washed by H2O, NaHCO3 and brine. The collected organic fractions were concentrated and purified by FCC (PE/EA=1/4) to give the title compound (53%). [M+H] Calc'd for C17H13ClN4, 309. Found, 309.

Provenance & Evidence