1-(Bromomethyl)naphthalene → HCID 90408139, compound

HRID 2277561Notes

Reaction equation

HRID 2277561 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.Br[CH2:15][C:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][CH:17]=1>>[C:16]1([CH2:15][N:1]2[CH:5]=[C:4]([C:6]3[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=3)[N:3]=[CH:2]2)[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 178510201HCID 178510201, compound

Product 1

HCID 90408139HCID 90408139, compound

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile (PREPARATION 4) and 1-(bromomethyl)naphthalene according to the procedure for the preparation of Example 43, part A using room temp. [M+H] Calc'd for C20H14N4, 311. Found, 311.

Sources & evidence

ORD record
ord-0cf1ce5154fb4961a2c072e496cc3e84
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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