2-(Trifluoromethoxy)benzyl bromide → HCID 90407261, compound

HRID 2277562Notes

Reaction equation

HRID 2277562 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.[F:14][C:15]([F:26])([F:25])[O:16][C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19]Br>>[F:14][C:15]([F:25])([F:26])[O:16][C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 27772542-(Trifluoromethoxy)benzyl bromideHCID 178510201HCID 178510201, compound

Product 1

HCID 90407261HCID 90407261, compound

Procedure

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile (PREPARATION 4) and 2-(trifluoromethoxy)benzyl bromide according to the procedure for the preparation of Example 43, part A using room temp. [M+H] Calc'd for C17H11F3N4O, 345. Found, 345.

Sources & evidence

ORD record
ord-fb5e3adf080748b99e5794340434975c
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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