4-Fluoro-1-naphthaleneboronic Acid (contains varying amounts of Anhydride) → HCID 90407426, compound

HRID 2277569Notes

Reaction equation

HRID 2277569 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[F:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:20](B(O)O)=[CH:19][CH:18]=1>>[F:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:20]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 27826754-Fluoro-1-naphthaleneboronic Acid (contains varying amounts of Anhydride)HCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407426HCID 90407426, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile (PREPARATION 2) and 4-fluoronaphthalene-1-boronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H13FN4, 329. Found, 329.

Sources & evidence

ORD record
ord-62851d1ee6014359b24a1d26e33be71a
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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