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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277572Generated: October 31, 2026

Potassium Carbonate → HCID 90407321, compound

https://huagongshe.com/reaction/2277572

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantChloromethyl acetateHCID 69366—
ReactantHCID 90407535HCID 90407535—
SolventDimethylformamideHCID 6228—
ProductHCID 90407321HCID 9040732115%

Reaction Steps

The title compound was prepared in 15% yield from 2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(2H-tetrazol-5-yl)pyridine (Example 129), chloromethyl acetate and potassium carbonate in DMF. 1H NMR (400 MHz, DMSO): δ 2.12 (3H, s), 5.41 (2H, s), 6.67 (2H, s), 7.27-7.29 (1H, m), 7.38-7.41 (2H, m), 7.53-7.55 (1H, m), 7.81 (1H, s), 7.94 (1H, s), 8.51 (1H, s), 8.68 (1H, d, J=5.0 Hz). [M+H] Calc'd for C19H16ClN7O2, 410. Found, 410.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-926160dd38c4418091789a6cdc0b35c4
Source noteuspto-grants-2015_09