HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 90407321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Chloromethyl acetate | HCID 69366 | — |
| Reactant | HCID 90407535 | HCID 90407535 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 90407321 | HCID 90407321 | 15% |
Reaction Steps
The title compound was prepared in 15% yield from 2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(2H-tetrazol-5-yl)pyridine (Example 129), chloromethyl acetate and potassium carbonate in DMF. 1H NMR (400 MHz, DMSO): δ 2.12 (3H, s), 5.41 (2H, s), 6.67 (2H, s), 7.27-7.29 (1H, m), 7.38-7.41 (2H, m), 7.53-7.55 (1H, m), 7.81 (1H, s), 7.94 (1H, s), 8.51 (1H, s), 8.68 (1H, d, J=5.0 Hz). [M+H] Calc'd for C19H16ClN7O2, 410. Found, 410.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-926160dd38c4418091789a6cdc0b35c4 |
| Source note | uspto-grants-2015_09 |