2-Pyrrolidone → HCID 86679117, compound

HRID 2277644Notes

Reaction equation

HRID 2277644 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][C:2]1=[O:6].[Br:7][C:8]1[CH:9]=[N:10][CH:11]=[C:12]([CH2:14]Cl)[CH:13]=1>>[Br:7][C:8]1[CH:13]=[C:12]([CH2:14][N:1]2[CH2:5][CH2:4][CH2:3][C:2]2=[O:6])[CH:11]=[N:10][CH:9]=1

Participants

3

Reactant 2

HCID 120252-PyrrolidoneHCID 117012593-Bromo-5-(chloromethyl)pyridine

Product 1

HCID 86679117HCID 86679117, compound

Procedure

In analogy to the procedure described for the preparation of intermediates B-1 [B], pyrrolidin-2-one has been coupled to 3-bromo-5-chloromethyl-pyridine (intermediate B-1 [A]) to yield the title compound as a white solid. MS: 251.1, 257.1 (M+H+).

Sources & evidence

ORD record
ord-32e76ec2ce874ca489ae8b84fb8dc5d8
Source dataset
uspto-grants-2015_09
Patent number
US09133158B2

Reaction notes

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