2-Piperidone → HCID 86679118, compound

HRID 2277645Notes

Reaction equation

HRID 2277645 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=[O:7].[Br:8][C:9]1[CH:10]=[N:11][CH:12]=[C:13]([CH2:15]Cl)[CH:14]=1>>[Br:8][C:9]1[CH:14]=[C:13]([CH2:15][N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][C:2]2=[O:7])[CH:12]=[N:11][CH:10]=1

Participants

3

Reactant 2

HCID 126652-PiperidoneHCID 117012593-Bromo-5-(chloromethyl)pyridine

Product 1

HCID 86679118HCID 86679118, compound

Procedure

In analogy to the procedure described for the preparation of intermediates B-1 [B], piperidin-2-one has been coupled to 3-bromo-5-chloromethyl-pyridine (intermediate B-1 [A]) to yield the title compound as a colorless oil. MS: 269.2, 271.2 (M+H+).

Sources & evidence

ORD record
ord-21d25a416e0e4994bc909c1f974756a7
Source dataset
uspto-grants-2015_09
Patent number
US09133158B2

Reaction notes

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