HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenol → N2,N4-bis(3-hydroxyphenyl)-2,4-pyrimidinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | R-112 | HCID 9904854 | — |
| Product | N2,N4-bis(3-hydroxyphenyl)-2,4-pyrimidinediamine | HCID 10149490 | — |
Reaction Steps
In a manner analogous to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,4-dichloropyrimidine with 3-hydroxyaniline gave N2,N4-bis(3-hydroxyphenyl)-2,4-pyrimidinediamine. LCMS: ret. time: 16.21 min.; purity: 100%; MS (m/e): 295 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133133B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-19a0f1e80bc34b4f89b529a2db69adf6 |
| Source note | uspto-grants-2015_09 |