Hydrochloric Acid → HCID 117628857, compound

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Reaction Steps

A solution of ((6R)-6-[5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl]-2,2,3,3,9,9-hexamethyl-4-oxa-8-thionia-7-aza-3-siladecan-8-olate (12.7 g, 26.7 mmol) in MeOH (26 mL) cooled to 0° C. was treated with a 4 N hydrogen chloride solution (46.7 mL, 187 mmol) for 2 hours. The solvent was evaporated under reduced pressure, after which toluene was added and the co-solvent mixture was evaporated under reduce pressure to afford a white solid characterized as the title compound. 1H NMR ((CD3)2SO) δ 8.50 (1H), 7.17 (1H), 7.04 (1H), 5.70 (1H), 5.65 (1H), 4.53 (1H), 3.80-3.71 (2H), 3.65 (4H), 1.15 (3H), 0.73 (3H).

Provenance & Evidence