Dimethylformamide dimethyl acetal → HCID 67513835, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1-(2-methyl-3-furanyl)-2-(4-pyridinyl)ethanone (1.006 g, 5 mmol) in N,N-dimethylformamide dimethyl acetal (0.664 ml, 5 mmol) was heated at 100° C. for 2 hours. The mixture was cooled to room temperature and the solvent was evaporated. The residue was partitioned between ethyl acetate and water. The organic phase was separated, washed with water and brine, dried and evaporated to give the title compound as an oil (1.1 g, 86%). LC/MS [M+H]+=257.

Provenance & Evidence