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HRID2278536

反应详情

EQUATION

反应方程式

HRID 2278536 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(B2OC(C)(C)C(C)(C)O2)ccn1
HCID44754862

2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

C12H18BNO3

结构：O=C(Cc1nc(Cl)cc(=O)[nH]1)N1CCc2c(F)cccc21
HCID136378674

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2cc(=O)[nH]c(CC(=O)N3CCc4c(F)cccc43)n2)ccn1
HCID136098479

未命名化合物

收率 60.7%

PROCEDURE

实验过程

The product is prepared by following the procedure described in example 12b using 100 mg of 2-[2-(4-fluoro-2,3-dihydroindol-1-yl)-2-oxoethyl]-6-chloro-3H-pyrimidin-4-one and 160 mg of 2-methoxypyridine-4-boronic acid pinacol ester. 75 mg of 2-[2-(4-fluoro-2,3-dihydroindol-1-yl)-2-oxoethyl]-6-(2-methoxypyridin-4-yl)-3H-pyrimidin-4-one are obtained in the form of a beige solid, the characteristics of which are the following:

WORKUP

后处理

  1. customThe product is prepared