Potassium Carbonate → HCID 68281537, compound

Participants

Reaction Conditions

Reaction Steps

2 g of 3-bromo-2-methylpropene, 1.9 g of potassium carbonate and 570 mg of sodium hydride (dispersion in oil at 60%) are added to a solution of 3 g of N-(2-bromo-3-fluorophenyl)acetamide in 25 ml of toluene. The reaction mixture is placed under an argon atmosphere and heated at 75° C. for 16 hours. The reaction mixture is treated with a mixture of water and ethyl acetate, and the organic phase is then washed with water and a saturated sodium chloride solution, dried over magnesium sulfate, filtered, and concentrated under reduced pressure, so as to give 3.8 g of N-(2-bromo-3-fluorophenyl)-N-(2-methylallyl)acetamide.

Provenance & Evidence