HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S,E)-3-(pent-2-enoyl)-4-phenyloxazolidin-2-one → 4-((4S,5S)-5-(Cyanomethyl)-4-ethyl-1-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S,E)-3-(pent-2-enoyl)-4-phenyloxazolidin-2-one | HCID 11096863 | — |
| Reactant | 4-((4S,5S)-5-(cyanomethyl)-1-(4-hydroxyphenyl)-4-methyl-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile | HCID 86719429 | — |
| Product | 4-((4S,5S)-5-(Cyanomethyl)-4-ethyl-1-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile | HCID 86719435 | — |
Reaction Steps
4-((4S,5S)-5-(Cyanomethyl)-4-ethyl-1-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile was prepared from (S,E)-3-(pent-2-enoyl)-4-phenyloxazolidin-2-one following the procedure for the preparation of 4-((4S,5S)-5-(cyanomethyl)-1-(4-hydroxyphenyl)-4-methyl-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile (91G): LC-MS [M+H] 331.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133163B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-37bf35e670d24378bb9184d6171145ad |
| Source note | uspto-grants-2015_09 |