HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → (2-Methylpyrimidin-5-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 5-(Azidomethyl)-2-methylpyrimidine | HCID 54595022 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (2-Methylpyrimidin-5-yl)methanamine | HCID 21294601 | — |
Reaction Steps
A mixture of 5-(azidomethyl)-2-methylpyrimidine (55 mg, 0.00037 mol) in ethyl acetate (20 mL, 0.2 mol), and 10% Pd—C (70 mg) was stirred under H2 (1 atm) for 2 hr. The catalyst was filtered off and filtrate was concentrated in vacuo to afford a white solid. LC/MS m/e 124.3 (M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133122B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ba85c4aa834c45a2993f12ffeb93fcd4 |
| Source note | uspto-grants-2015_09 |