HCID 14365061, compound → HCID 90308267, compound

Participants

Reaction Steps

1.6 g (3.00 mmol) Boc-D-Phe(4-NO2)-Phe(4-NO2)—OMe (4a) was dissolved in 150 ml of 90% acetic acid. Then, 160 mg Pd—C was added, purged 3× and hydrogenated overnight at RT. After filtration of the suspension, the solvent was removed in vacuo. The residue was taken up in sat. NaHCO3 soln./EtOAc and the organic phase was washed 3× with sat. NaHCO3 soln. and 2× with sat. NaCl soln. The organic phase was dried with MgSO4, followed by filtration and removal of the solvent in vacuo.

Provenance & Evidence