反应详情

250 mg 4-[4-(4-benzyl-2,2,5,5-tetramethyl-piperazin-1-ylmethyl)-3-methyl-1-(tetra-hydro-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol was dissolved in 20 ml methanol and purged with argon. 25 mg Palladium (10% on charcoal) were added and the mixture was hydrogenated at r.t. for 30 min. The catalyst was filtered off and the solvents were evaporated. 150 mg (72%) of the title compound were obtained.

1. custompurged with argon
2. addition25 mg Palladium (10% on charcoal) were added
3. filtrationThe catalyst was filtered off
4. customthe solvents were evaporated