1-Benzyl-5-ethyl-2,2,5-trimethyl-piperazine → HCID 178436806, compound

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Reaction Steps

4-[4-(2-ethyl-2,5,5-trimethyl-piperazin-1-ylmethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol was synthesized in analogy to Example 49 (4-[3-Methyl-4-(2,2,5,5-tetramethyl-piperazin-1-ylmethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol) starting from 3-methyl-1-(tetrahydro-pyran-2-yl)-6-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid and 1-benzyl-5-ethyl-2,2,5-trimethyl-piperazine.

Provenance & Evidence