HCID 51341942, compound → HCID 178436580, compound

HRID 2279124Notes

Reaction equation

HRID 2279124 reaction equation
[CH2:1]([C:3]1([CH2:30][CH3:31])[CH2:8][N:7]([CH2:9][C:10]2[CH:15]=[C:14]([C:16]3[CH:21]=[CH:20][C:19]([OH:22])=[C:18](F)[CH:17]=3)[N:13]=[C:12]3[NH:24][N:25]=[C:26]([CH3:27])[C:11]=23)[C:6]([CH3:29])([CH3:28])[CH2:5][NH:4]1)[CH3:2].[Cl:32]C1C=C(O)C=CC=1B1OCC(C)(C)CO1>>[Cl:32][C:17]1[CH:18]=[C:19]([OH:22])[CH:20]=[CH:21][C:16]=1[C:14]1[N:13]=[C:12]2[NH:24][N:25]=[C:26]([CH3:27])[C:11]2=[C:10]([CH2:9][N:7]2[CH2:8][C:3]([CH2:30][CH3:31])([CH2:1][CH3:2])[NH:4][CH2:5][C:6]2([CH3:29])[CH3:28])[CH:15]=1

Participants

3

Reactant 2

HCID 51341942HCID 51341942, compoundHCID 178436581HCID 178436581, compound

Product 1

HCID 178436580HCID 178436580, compound

Procedure

The title compound was synthesized in a similar manner as Example 58 (4-[4-(5,5-Diethyl-2,2-dimethyl-piperazin-1-ylmethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl]-2-fluoro-phenol) employing 3-chloro-4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenol in step (b).

Sources & evidence

ORD record
ord-159e20a07b3f4aa3aa14e898796f194a
Source dataset
uspto-grants-2015_09
Patent number
US09133181B2

Reaction notes

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