HCID 90014026, compound → HCID 90013940, compound

Participants

Reaction Steps

1.44 g of 4-(4-benzyl-2,2,5,5-tetramethyl-piperazin-1-ylmethyl)-6-(4-methoxymethoxy-phenyl)-3-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine were dissolved in 16 ml dichloromethane and purged with argon. 1.44 g Palladium (10% on charcoal) were added and the mixture was hydrogenated at r.t. for 5 h. The catalyst was filtered off using celite and the solvents were evaporated. 1.13 g (93%) of the crude title compound were obtained, which were used in the next step without further purification.

Provenance & Evidence