Acetone Cyanohydrin → HCID 308103, compound

HRID 2279183Notes

Reaction equation

HRID 2279183 reaction equation
[CH2:1]([N:8]1[CH2:17][C:16]([CH3:19])([CH3:18])[NH:15][CH2:14][C:9]21[CH2:13]CC[CH2:10]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CC(N)(C)CN.CC(C)(O)C#N>>[CH2:1]([N:8]1[CH2:17][C:16]([CH3:19])([CH3:18])[NH:15][CH2:14][C:9]1([CH3:13])[CH3:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 6406Acetone CyanohydrinHCID 131282-MethylpropylenediamineHCID 64842474HCID 64842474, compound

Product 1

HCID 308103HCID 308103, compound

Procedure

1-Benzyl-2,2,5,5-tetramethyl-piperazine was synthesized in analogy to 6-benzyl-8,8-dimethyl-6,9-diaza-spiro[4.5]decane starting from 2-methyl-propane-1,2-diamine and acetone cyanohydrin.

Sources & evidence

ORD record
ord-64fa662530864592b4165d46284c7a69
Source dataset
uspto-grants-2015_09
Patent number
US09133181B2

Reaction notes

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