Hydrochloric Acid → HCID 60198466, compound

Participants

Reaction Steps

To a solution of 106 (106 mg, 0.204 mmol) in MeOH (2 mL) and a small amount of DCM was added 4 M HCl in dioxane (764 μL, 3.06 mmol). The reaction was stirred at RT for 4 h. The reaction was concentrated and purified by reverse phase column chromatography (SP4) eluting with a MeCN/H2O gradient (0-80% MeCN) to afford 50.7 mg (54.5%) of I-17: LCMS (ACPI-pos) m/z 420.3 (M+H)+.

Provenance & Evidence