Tetrabutylammonium Fluoride → HCID 68294680, compound

Participants

Reaction Steps

To a solution of 132 (35 mg, 0.0650 mmol) in THF (1 mL) cooled to 0° C. was added TBAF (91 μL, 0.0911 mmol) and reaction was stirred at RT for 2 h. The reaction was concentrated and the resulting residue was purified on a reverse phase column (SP4) eluting with a MeCN/H2O gradient (5 to 95% MeCN) to afford 17.2 mg (62.4%) of I-20: LCMS (ACPI-pos) m/z 424.1 (M+H)+.

Provenance & Evidence