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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2279496Generated: October 31, 2026

2-Methyl-2H-pyrazol-3-ylamine → N-(2-ethoxypyridin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine

https://huagongshe.com/reaction/2279496

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-2H-pyrazol-3-ylamineHCID 136927—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
ProductN-(2-ethoxypyridin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amineHCID 68294219—

Reaction Steps

N-(2-ethoxypyridin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine (186) was prepared in accord with the procedures described in steps 1 to 4 of example 25 except in step 1, 1-methyl-1H-pyrazol-5-amine was replaced with 2-ethoxypyridin-4-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133187B2
Source datasetuspto-grants-2015_09
ORD IDord-0f8aeb369d8a43eebf03dfcae56e1867
Source noteuspto-grants-2015_09