Methanol → HCID 60198781, compound

Participants

Reaction Steps

To a stirred solution of 362 (102 mg, 0.1810 mmol) in DCM (1.8 mL) at RT in a capped flask was added MeOH (180 μL) followed by 4M HCl dioxane solution (452.5 μL, 1.810 mmol). After 2 h the reaction was diluted with Et2O (5 mL) which produced a coarse yellow precipitate. The solid was filtered off and washed with generous amounts of ether to afford 80 mg (80%) of I-93 as a pale yellow solid which was dried under high vacuum: MS m/z (APCI-pos) M+1=463.4.

Provenance & Evidence