Water → HCID 86705551, compound

Participants

Reaction Steps

To a stirred solution of 364 (750 mg, 1.88 mmol) in THF (25 mL) and acetone (5 mL) at RT was added NaI (1411 mg, 9.41 mmol) and stirring was continued overnight. The mixture was poured into water, extracted with EtOAc, washed with brine, dried (MgSO4), and concentrated to afford 810 mgs (100%) of (R)-tert-butyl 1-(3,4-dichlorophenyl)-3-iodopropylcarbamate (366).

Provenance & Evidence