Hydrochloric Acid → HCID 86705557, compound

Participants

Reaction Steps

To a stirred solution of 374 (395 mg, 1.03 mmol) in DCM (5 mL) was added a 4M HCl in dioxane (1.03 mL, 4.13 mmol) and stirring was continued overnight. The mixture was diluted with ether, filtered, dried and concentrated to afford 248 mg (75%) of (R)-1-(3,4-dichlorophenyl)-3-(methylsulfonyl)propan-1-amine hydrochloride (376) as white solid.

Provenance & Evidence